MetaCyc Pathway: dTDP-N-acetylviosamine biosynthesis in Pseudomonas fluorescens FW300-N1B4

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Reactions and Genes Fusidic 0.125 mg/ml
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Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24)
Pf1N1B4_1222 -0.0
Pf1N1B4_2533 N.D.
Pf1N1B4_341 -0.6
Pf1N1B4_5938 +1.5
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O (EC 4.2.1.46)
Pf1N1B4_1223 -0.2
Pf1N1B4_343 +0.6
Pf1N1B4_5885 -0.4
Pf1N1B4_5939 +0.7
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (in reverse):
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + L-glutamate→dTDP-viosamine + 2-oxoglutarate (EC 2.6.1.33)
No genes
dTDP-viosamine + acetyl-CoA→dTDP-N-acetylviosamine + coenzyme A + H+ (EC 2.3.1.209)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information