MetaCyc Pathway: 3-phenylpropanoate degradation in Sphingomonas koreensis DSMZ 15582

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Reactions and Genes Choline chloride 40 mM
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3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
Ga0059261_0515 +0.1
Ga0059261_0837 -0.1
Ga0059261_2159 -0.0
Ga0059261_2668 +0.1
Ga0059261_2803 -0.1
Ga0059261_2815 -0.0
Ga0059261_2818 +0.1
Ga0059261_2827 -0.1
Ga0059261_2840 +0.0
Ga0059261_2847 -0.1
Ga0059261_2858 -0.2
Ga0059261_2861 +0.0
Ga0059261_2887 +0.1
Ga0059261_2902 -0.0
Ga0059261_2908 -0.1
Ga0059261_3683 -1.1
Ga0059261_3685 -3.0
Ga0059261_3986 +0.1
Ga0059261_4214 -0.1
Ga0059261_4222 -0.1
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
Ga0059261_0837 -0.1
Ga0059261_2534 -1.0
Ga0059261_2816 -0.0
Ga0059261_2827 -0.1
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
Ga0059261_0982 -0.2
Ga0059261_1483 -0.3
Ga0059261_2108 +0.1
Ga0059261_2160 +0.0
Ga0059261_2808 -0.1
Ga0059261_2835 +0.0
Ga0059261_2867 -0.1
Ga0059261_2877 -0.1
Ga0059261_2888 -0.0
Ga0059261_3284 -0.4
Benzoyl-CoA 3-monooxygenase:
benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
Ga0059261_0509 -0.0
Maleylpyruvate isomerase:
3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
Ga0059261_0507 +0.2
Ga0059261_2015 +0.1
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
Ga0059261_0508 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information