MetaCyc Pathway: adipate degradation in Sphingomonas koreensis DSMZ 15582

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Reactions and Genes Vanillin 0.25 mM
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Succinate--CoA ligase (ADP-forming):
adipate + ATP + coenzyme A→adipoyl-CoA + ADP + phosphate (EC 6.2.1.5)
Ga0059261_1340 N.D.
Ga0059261_2278 N.D.
adipoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-5-carboxy-2-pentenoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
Ga0059261_0740 -0.0
Ga0059261_0847 +0.2
Ga0059261_1309 -0.0
Ga0059261_3633 -0.1
Ga0059261_3793 +0.1
Enoyl-CoA hydratase (in reverse):
(2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA (EC 4.2.1.17)
Ga0059261_0515 +0.2
Ga0059261_0837 -0.1
Ga0059261_2159 -0.4
Ga0059261_2668 -0.0
Ga0059261_2803 +0.0
Ga0059261_2815 +0.0
Ga0059261_2818 +0.1
Ga0059261_2827 -0.1
Ga0059261_2840 +0.1
Ga0059261_2847 -0.2
Ga0059261_2858 -0.0
Ga0059261_2861 +0.0
Ga0059261_2887 +0.0
Ga0059261_2902 -0.1
Ga0059261_2908 +0.0
Ga0059261_3683 -1.2
Ga0059261_3685 -2.4
Ga0059261_3986 +0.1
Ga0059261_4214 -0.8
Ga0059261_4222 -0.1
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+ (EC 1.1.1.35)
Ga0059261_0837 -0.1
Ga0059261_2534 -0.7
Ga0059261_2816 +0.1
Ga0059261_2827 -0.1
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA (EC 2.3.1.174)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information