MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Sphingomonas koreensis DSMZ 15582

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Reactions and Genes Gentamicin 0.015 mg/ml
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
Ga0059261_0514 +0.0
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
Ga0059261_0515 -0.0
3-hydroxyacyl-CoA dehydrogenase:
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+ (EC 1.1.1.35)
Ga0059261_0837 -0.1
Ga0059261_2534 -0.6
Ga0059261_2816 -0.0
Ga0059261_2827 +0.0
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
Ga0059261_0982 +0.0
Ga0059261_1483 -2.0
Ga0059261_2108 -0.1
Ga0059261_2160 -0.1
Ga0059261_2808 -0.1
Ga0059261_2835 +0.0
Ga0059261_2867 -0.1
Ga0059261_2877 -0.0
Ga0059261_2888 +0.0
Ga0059261_3284 -0.4
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+ (EC 3.1.2.23)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information