MetaCyc Pathway: 4-ethylphenol degradation (anaerobic) in Sphingomonas koreensis DSMZ 15582

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Reactions and Genes Gentamicin 0.005 mg/ml
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1-ethyl-4-hydroxybenzene + an oxidized electron carrier + H2O→S-1-(4-hydroxyphenyl)-ethanol + a reduced two electron carrier
No genes
S-1-(4-hydroxyphenyl)-ethanol + NAD+→4-hydroxyacetophenone + NADH + H+
No genes
4-hydroxyacetophenone + ATP + CO2 + 2 H2O→4-hydroxybenzoyl-acetate + AMP + 3 H+ + 2 phosphate
No genes
4-hydroxybenzoyl-acetate + ATP + coenzyme A→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + AMP + diphosphate
No genes
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
Ga0059261_0982 -0.2
Ga0059261_1483 -1.3
Ga0059261_2108 -0.2
Ga0059261_2160 +0.1
Ga0059261_2808 -0.1
Ga0059261_2835 -0.0
Ga0059261_2867 +0.0
Ga0059261_2877 +0.0
Ga0059261_2888 +0.1
Ga0059261_3284 -0.2
4-hydroxybenzoyl-CoA + 2 H+ + a reduced 2[4Fe-4s] ferredoxin→benzoyl-CoA + an oxidized 2[4Fe-4s] ferredoxin + H2O (EC 1.1.7.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information