| Reactions and Genes | Sisomicin 0.00390625 mg/ml |
|---|
| remove |
| a fatty acid + ATP + coenzyme A→an acyl-CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| Sama_0032 (fadB) | -0.3 |
| Sama_1378 | +0.1 |
| Sama_1379 | -0.0 |
| Sama_2167 (fadJ) | -1.6 |
| Sama_3052 | +0.2 |
| Sama_3135 | -0.2 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| Sama_0032 (fadB) | -0.3 |
| Sama_2167 (fadJ) | -1.6 |
| a 2,3,4-saturated 3-oxoacyl-CoA + H2O→a 3-oxoacid + coenzyme A + H+ |
| No genes |
| a 3-oxoacid + H+→a methyl ketone + CO2 (spontaneous) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information