MetaCyc Pathway: L-tyrosine biosynthesis I in Enterobacter sp. TBS_079

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Reactions and Genes mutant library grown in Supernatant; Pseudomonas frederiksbergensis TBS_004 grown in LB
remove
Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
MPMX20_01201 +0.0
MPMX20_03466 -0.1
MPMX20_03468 -0.0
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH
(EC 1.3.1.12)
MPMX20_03468 -0.0
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
MPMX20_00272 -0.1
MPMX20_00609 +0.1
MPMX20_00612 -0.0
MPMX20_01049 +0.0
MPMX20_01059 +0.1
MPMX20_01157 -0.1
MPMX20_01586 -1.1
MPMX20_02048 +0.1
MPMX20_02230 +0.1
MPMX20_02425 -3.4
MPMX20_03003 -0.1
MPMX20_03220 -0.2
MPMX20_04048 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information