MetaCyc Pathway: L-tryptophan degradation XIII (reductive Stickland reaction) in Enterobacter sp. TBS_079

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Reactions and Genes mutant library grown in Supernatant; Pseudomonas lini TBS_031 grown in LB
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Aspartate transaminase:
L-tryptophan + 2-oxoglutarate→(indol-3-yl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27)
MPMX20_00609 -0.0
MPMX20_00612 -0.0
MPMX20_01049 -0.0
MPMX20_01059 -0.0
MPMX20_01157 -0.1
MPMX20_01586 -0.7
MPMX20_02048 +0.1
MPMX20_02230 +0.1
MPMX20_02425 -2.2
MPMX20_03220 -0.0
MPMX20_04048 -0.0
Indolelactate dehydrogenase (in reverse):
(indol-3-yl)pyruvate + NADH + H+→(R)-3-(indol-3-yl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(indol-3-yl)lactate + 3-(indol-3-yl)acryloyl-CoA→3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA (EC 2.8.3.17)
No genes
3-(indol-3-yl)acrylate + a reduced electron-transfer flavoprotein→3-(1H-indol-3-yl)propanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(indol-3-yl)lactoyl-CoA→3-(indol-3-yl)acryloyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information