MetaCyc Pathway: superpathway of adenosylcobalamin salvage from cobinamide II in Rhodopseudomonas palustris CGA009

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Reactions and Genes PM_N2O butyrate and nitrate 0.1 mM
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Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase:
5,6-dimethylbenzimidazole + β-nicotinate D-ribonucleotide→α-ribazole 5'-phosphate + nicotinate + H+ (EC 2.4.2.21)
TX73_003685 -2.7
TX73_010790 -0.2
Cob(I)yrinic acid a,c-diamide adenosyltransferase:
cob(II)inamide + a [corrinoid adenosyltransferase]→[corrinoid adenosyltranferase]-cob(II)inamide (EC 2.5.1.17)
TX73_003710 -0.3
TX73_024685 -0.0
Cob(I)yrinic acid a,c-diamide adenosyltransferase:
2 [corrinoid adenosyltranferase]-cob(II)inamide + a [reduced flavoprotein]→2 [corrinoid adenosyltranferase]-cob(I)inamide + an [oxidized flavoprotein] + 2 H+ (spontaneous) (EC 2.5.1.17)
TX73_003710 -0.3
TX73_024685 -0.0
Cob(I)yrinic acid a,c-diamide adenosyltransferase:
2 [corrinoid adenosyltranferase]-cob(I)inamide + 2 ATP + 2 H+→2 adenosylcobinamide + 2 a [corrinoid adenosyltransferase] + 2 triphosphate (EC 2.5.1.17)
TX73_003710 -0.3
TX73_024685 -0.0
Adenosylcobinamide hydrolase:
adenosylcobinamide + H2O→adenosylcobyrate + (R)-1-aminopropan-2-ol (EC 3.5.1.90)
No genes
Adenosylcobinamide-phosphate synthase:
adenosylcobyrate + (R)-1-amino-2-propanol O-2-phosphate + ATP→adenosyl-cobinamide phosphate + ADP + H+ + phosphate (EC 6.3.1.10)
TX73_003720 N.D.
Adenosylcobinamide-phosphate guanylyltransferase:
adenosyl-cobinamide phosphate + GTP + H+→adenosylcobinamide-GDP + diphosphate (EC 2.7.7.62)
TX73_003695 N.D.
Adenosylcobinamide-GDP ribazoletransferase:
adenosylcobinamide-GDP + α-ribazole 5'-phosphate→adenosylcobalamin 5'-phosphate + GMP + H+ (EC 2.7.8.26)
TX73_006455 -3.6
TX73_010795 -0.2
Alpha-ribazole phosphatase:
adenosylcobalamin 5'-phosphate + H2O→adenosylcobalamin + phosphate (EC 3.1.3.73)
TX73_005110 -3.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information