MetaCyc Pathway: adenosylcobalamin biosynthesis from adenosylcobinamide-GDP I in Rhodopseudomonas palustris CGA009

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Reactions and Genes PM_N2O butyrate and nitrate 0.1 mM
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Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase:
5,6-dimethylbenzimidazole + β-nicotinate D-ribonucleotide→α-ribazole 5'-phosphate + nicotinate + H+
(EC 2.4.2.21)
TX73_003685 -2.5
TX73_010790 -0.3
Adenosylcobinamide-GDP ribazoletransferase:
α-ribazole 5'-phosphate + adenosylcobinamide-GDP→adenosylcobalamin 5'-phosphate + GMP + H+
(EC 2.7.8.26)
TX73_006455 -1.7
TX73_010795 -0.1
Alpha-ribazole phosphatase:
adenosylcobalamin 5'-phosphate + H2O→adenosylcobalamin + phosphate
(EC 3.1.3.73)
TX73_005110 -2.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information