MetaCyc Pathway: isoniazid activation in Dyella japonica UNC79MFTsu3.2

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Reactions and Genes D-Glucosamine Hydrochloride (N)
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2 isoniazid + hydrogen peroxide→2 isonicotinate acyl radical + 2 diazene + 2 H2O
ABZR86_RS00615 -4.3
2 isonicotinate acyl radical + NAD+ + NADH→2 isonicotinate acyl-NADH adduct + H+ (spontaneous)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information