MetaCyc Pathway: superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes copper (II) chloride 3 mM
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Phosphoglucomutase (in reverse):
D-glucopyranose 6-phosphate→α-D-glucopyranose 1-phosphate (EC 5.4.2.2)
Pf6N2E2_1059 -1.1
Pf6N2E2_3357 N.D.
Pf6N2E2_4374 +0.3
UTP-monosaccharide-1-phosphate uridylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + UTP→UDP-α-D-glucose + diphosphate (EC 2.7.7.64; 2.7.7.9)
Pf6N2E2_445 -6.8
UDP-glucose 4-epimerase:
UDP-α-D-glucose→UDP-α-D-galactose (EC 5.1.3.2)
Pf6N2E2_203 -0.1
Pf6N2E2_2509 +0.0
Pf6N2E2_2512 N.D.
Pf6N2E2_2615 -0.4
Pf6N2E2_4243 -0.2
Pf6N2E2_489 +0.2
Pf6N2E2_4908 +0.1
UDP-glucose 6-dehydrogenase:
UDP-α-D-glucose + 2 NAD+ + H2O→UDP-α-D-glucuronate + 2 NADH + 3 H+ (EC 1.1.1.22)
Pf6N2E2_1151 +0.2
Pf6N2E2_125 -0.1
Pf6N2E2_2513 +0.4
UDP-galactopyranose mutase:
UDP-α-D-galactose→UDP-α-D-galactofuranose (EC 5.4.99.9)
No genes
UDP-glucuronate 4-epimerase:
UDP-α-D-glucuronate→UDP-α-D-galacturonate (EC 5.1.3.6)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information