MetaCyc Pathway: thiamine diphosphate salvage II in Desulfovibrio vulgaris Miyazaki F

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Reactions and Genes Defined MoLS4
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Hydroxymethylpyrimidine kinase:
4-amino-2-methyl-5-pyrimidinemethanol + ATP→4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H+ (EC 2.7.1.49)
DvMF_1376 N.D.
Hydroxyethylthiazole kinase:
5-(2-hydroxyethyl)-4-methylthiazole + ATP→4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ (EC 2.7.1.50)
DvMF_3006 -0.2
Phosphomethylpyrimidine kinase:
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP→4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP (EC 2.7.4.7)
DvMF_1376 N.D.
Thiamine-phosphate diphosphorylase:
4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)thiazole + H+→thiamine phosphate + diphosphate (EC 2.5.1.3)
DvMF_0797 -2.2
DvMF_3007 (thiE) +0.0
Thiamine-phosphate kinase:
thiamine phosphate + ATP→thiamine diphosphate + ADP (EC 2.7.4.16)
DvMF_1966 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information