MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Burkholderia phytofirmans PsJN

Add experiment(s):


Reactions and Genes L-Phenylalanine (N)
remove
Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
BPHYT_RS02345 +0.2
BPHYT_RS03225 -0.1
BPHYT_RS03235 -0.6
BPHYT_RS03825 N.D.
BPHYT_RS06755 N.D.
BPHYT_RS06760 -0.8
BPHYT_RS08375 N.D.
BPHYT_RS08630 +0.1
BPHYT_RS09560 -0.3
BPHYT_RS10815 N.D.
BPHYT_RS11780 N.D.
BPHYT_RS13345 +0.5
BPHYT_RS13545 -1.0
BPHYT_RS14830 +0.6
BPHYT_RS17335 -2.5
BPHYT_RS17350 N.D.
BPHYT_RS20025 -1.0
BPHYT_RS25360 N.D.
BPHYT_RS25695 N.D.
BPHYT_RS27105 -0.1
BPHYT_RS27895 +0.5
BPHYT_RS28015 -0.1
BPHYT_RS28020 N.D.
BPHYT_RS28620 +0.5
BPHYT_RS35465 +0.3
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information