MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Burkholderia phytofirmans PsJN

Add experiment(s):


Reactions and Genes L-Phenylalanine (N)
remove
Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
BPHYT_RS02345 +0.2
BPHYT_RS03225 -0.1
BPHYT_RS03235 -0.6
BPHYT_RS03825 N.D.
BPHYT_RS06755 N.D.
BPHYT_RS06760 -0.8
BPHYT_RS08375 N.D.
BPHYT_RS08630 +0.1
BPHYT_RS09560 -0.3
BPHYT_RS10815 N.D.
BPHYT_RS11780 N.D.
BPHYT_RS13345 +0.5
BPHYT_RS13545 -1.0
BPHYT_RS14830 +0.6
BPHYT_RS17335 -2.5
BPHYT_RS17350 N.D.
BPHYT_RS20025 -1.0
BPHYT_RS25360 N.D.
BPHYT_RS25695 N.D.
BPHYT_RS27105 -0.1
BPHYT_RS27895 +0.5
BPHYT_RS28015 -0.1
BPHYT_RS28020 N.D.
BPHYT_RS28620 +0.5
BPHYT_RS35465 +0.3
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
BPHYT_RS03225 -0.1
BPHYT_RS06760 -0.8
BPHYT_RS09560 -0.3
BPHYT_RS13545 -1.0
BPHYT_RS34155 +0.4
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
BPHYT_RS02230 -0.2
BPHYT_RS03230 +0.2
BPHYT_RS08275 -0.0
BPHYT_RS09150 +0.3
BPHYT_RS09180 +0.1
BPHYT_RS09565 +0.0
BPHYT_RS17345 -0.1
BPHYT_RS21955 +0.5
BPHYT_RS29385 -0.6
benzoyl-CoA + H2O→benzoate + coenzyme A + H+
BPHYT_RS35455 N.D.
Benzoate--CoA ligase:
benzoate + ATP + coenzyme A→benzoyl-CoA + AMP + diphosphate (EC 6.2.1.25)
BPHYT_RS13365 -0.0
benzoyl-CoA + benzyl alcohol→benzyl benzoate + coenzyme A (EC 2.3.1.196)
No genes
benzyl benzoate + H2O→benzoate + benzyl alcohol + H+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information