MetaCyc Pathway: octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) in Dyella japonica UNC79MFTsu3.2

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Reactions and Genes Fusidic 0.4 mg/ml
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Beta-ketoacyl-acyl-carrier-protein synthase II:
an acetyl-[acp] + a malonyl-[acp] + H+→an acetoacetyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
ABZR86_RS06160 N.D.
ABZR86_RS13535 -1.0
ABZR86_RS21495 -0.3
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an acetoacetyl-[acp] + NADPH + H+→a (3R)-3-hydroxybutanoyl-[acp] + NADP+ (EC 1.1.1.100)
ABZR86_RS00075 -0.5
ABZR86_RS04030 -0.2
ABZR86_RS05810 +0.2
ABZR86_RS06170 N.D.
ABZR86_RS08895 +0.2
ABZR86_RS12860 -0.2
ABZR86_RS15390 -0.1
ABZR86_RS17250 +0.5
ABZR86_RS17295 -0.0
ABZR86_RS18340 +0.3
ABZR86_RS20540 -1.1
ABZR86_RS20760 -0.2
ABZR86_RS21075 +0.7
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxybutanoyl-[acp]→a (2E)-but-2-enoyl-[acp] + H2O (EC 4.2.1.59)
ABZR86_RS21635 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-but-2-enoyl-[acp] + NADPH + H+→a butanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
ABZR86_RS15885 -0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a butanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
ABZR86_RS06160 N.D.
ABZR86_RS13535 -1.0
ABZR86_RS21495 -0.3
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexanoyl-[acp] + NADP+ (EC 1.1.1.100)
ABZR86_RS00075 -0.5
ABZR86_RS04030 -0.2
ABZR86_RS05810 +0.2
ABZR86_RS06170 N.D.
ABZR86_RS08895 +0.2
ABZR86_RS12860 -0.2
ABZR86_RS15390 -0.1
ABZR86_RS17250 +0.5
ABZR86_RS17295 -0.0
ABZR86_RS18340 +0.3
ABZR86_RS20540 -1.1
ABZR86_RS20760 -0.2
ABZR86_RS21075 +0.7
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexanoyl-[acp]→a (2E)-hex-2-enoyl-[acp] + H2O (EC 4.2.1.59)
ABZR86_RS21635 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-hex-2-enoyl-[acp] + NADPH + H+→a hexanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
ABZR86_RS15885 -0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a hexanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
ABZR86_RS06160 N.D.
ABZR86_RS13535 -1.0
ABZR86_RS21495 -0.3
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctanoyl-[acp] + NADP+ (EC 1.1.1.100)
ABZR86_RS00075 -0.5
ABZR86_RS04030 -0.2
ABZR86_RS05810 +0.2
ABZR86_RS06170 N.D.
ABZR86_RS08895 +0.2
ABZR86_RS12860 -0.2
ABZR86_RS15390 -0.1
ABZR86_RS17250 +0.5
ABZR86_RS17295 -0.0
ABZR86_RS18340 +0.3
ABZR86_RS20540 -1.1
ABZR86_RS20760 -0.2
ABZR86_RS21075 +0.7
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctanoyl-[acp]→a (2E)-oct-2-enoyl-[acp] + H2O (EC 4.2.1.59)
ABZR86_RS21635 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-oct-2-enoyl-[acp] + NADPH + H+→an octanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
ABZR86_RS15885 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information