| Reactions and Genes | L-Asparagine (N) |
|---|
| remove |
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1) |
| BPHYT_RS00155 | -0.0 |
| BPHYT_RS04100 | N.D. |
| BPHYT_RS05430 | +0.3 |
| BPHYT_RS05975 | -0.2 |
| BPHYT_RS06770 | -0.1 |
| BPHYT_RS08040 | +0.1 |
| BPHYT_RS08950 | -2.0 |
| BPHYT_RS09580 | +0.6 |
| BPHYT_RS10265 | -0.4 |
| BPHYT_RS10440 | +0.3 |
| BPHYT_RS13065 | +0.0 |
| BPHYT_RS13450 | +0.2 |
| BPHYT_RS15405 | +0.1 |
| BPHYT_RS15820 | -0.1 |
| BPHYT_RS21060 | -1.1 |
| BPHYT_RS21560 | -0.1 |
| BPHYT_RS21610 | -0.2 |
| BPHYT_RS21730 | -0.1 |
| BPHYT_RS22065 | +0.2 |
| BPHYT_RS22425 | +0.1 |
| BPHYT_RS26535 | -0.0 |
| BPHYT_RS27000 | +0.1 |
| BPHYT_RS28370 | +0.1 |
| BPHYT_RS28685 | -0.1 |
| BPHYT_RS28695 | -0.1 |
| BPHYT_RS30590 | +0.7 |
| BPHYT_RS30680 | -0.0 |
| BPHYT_RS35285 | +0.2 |
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4) |
| BPHYT_RS12410 | N.D. |
L-aspartate oxidase:
L-aspartate + dioxygen→2-iminosuccinate + hydrogen peroxide + H+ (EC 1.4.3.16) |
| BPHYT_RS15640 | -0.1 |
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11) |
| BPHYT_RS33895 | N.D. |
Quinolinate synthase:
2-iminosuccinate + glycerone phosphate→quinolinate + phosphate + 2 H2O (EC 2.5.1.72) |
| BPHYT_RS15650 | +0.0 |
| L-aspartate 4-semialdehyde + pyruvate→(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H+ + H2O (EC 4.3.3.7) |
| BPHYT_RS07320 | -0.1 |
| BPHYT_RS12615 | -1.0 |
| BPHYT_RS29250 | -0.1 |
| BPHYT_RS30940 | +0.5 |
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+ (EC 1.1.1.3) |
| BPHYT_RS08955 | -5.3 |
Nicotinate-nucleotide diphosphorylase (carboxylating) (in reverse):
quinolinate + 2 H+ + 5-phospho-α-D-ribose 1-diphosphate→β-nicotinate D-ribonucleotide + CO2 + diphosphate (EC 2.4.2.19) |
| BPHYT_RS15645 | +0.1 |
Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+ (EC 2.7.1.39) |
| BPHYT_RS33645 | -5.0 |
Homoserine O-succinyltransferase:
L-homoserine + succinyl-CoA→O-succinyl-L-homoserine + coenzyme A (EC 2.3.1.46) |
| No genes |
Nicotinate-nucleotide adenylyltransferase:
β-nicotinate D-ribonucleotide + ATP + H+→nicotinate adenine dinucleotide + diphosphate (EC 2.7.7.18) |
| BPHYT_RS06395 | N.D. |
| (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+→(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ + H2O (EC 1.17.1.8) |
| BPHYT_RS16800 | N.D. |
NAD(+) synthase (glutamine-hydrolyzing):
nicotinate adenine dinucleotide + ATP + L-glutamine + H2O→NAD+ + AMP + L-glutamate + diphosphate + H+ (EC 6.3.5.1) |
| BPHYT_RS05480 | -0.1 |
NAD(+) synthase:
nicotinate adenine dinucleotide + ammonium + ATP→NAD+ + AMP + diphosphate + H+ (EC 6.3.1.5) |
| BPHYT_RS05480 | -0.1 |
| BPHYT_RS23720 | +0.1 |
Cystathionine gamma-synthase:
O-succinyl-L-homoserine + L-cysteine→L-cystathionine + H+ + succinate (EC 2.5.1.48) |
| BPHYT_RS13720 | +0.0 |
| BPHYT_RS33835 | -5.6 |
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase:
(S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O→N-succinyl-2-amino-6-ketopimelate + coenzyme A (EC 2.3.1.117) |
| BPHYT_RS12190 | N.D. |
Threonine synthase:
O-phospho-L-homoserine + H2O→L-threonine + phosphate (EC 4.2.3.1) |
| BPHYT_RS08960 | -5.7 |
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate (EC 4.4.1.13) |
| No genes |
Succinyldiaminopimelate transaminase (in reverse):
N-succinyl-2-amino-6-ketopimelate + L-glutamate→N-succinyl-L,L-2,6-diaminopimelate + 2-oxoglutarate (EC 2.6.1.17) |
| BPHYT_RS07695 | N.D. |
| BPHYT_RS12185 | -1.4 |
| BPHYT_RS14915 | -6.4 |
| BPHYT_RS15580 | -0.8 |
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-methionine + tetrahydropteroyl tri-L-glutamate (EC 2.1.1.14) |
| BPHYT_RS26655 | +0.3 |
Methionine synthase:
L-homocysteine + a 5-methyltetrahydrofolate→L-methionine + a tetrahydrofolate (EC 2.1.1.13) |
| BPHYT_RS02305 | -1.5 |
| BPHYT_RS02310 | -1.3 |
Succinyl-diaminopimelate desuccinylase:
N-succinyl-L,L-2,6-diaminopimelate + H2O→L,L-diaminopimelate + succinate (EC 3.5.1.18) |
| BPHYT_RS12200 | N.D. |
Diaminopimelate epimerase:
L,L-diaminopimelate→meso-diaminopimelate (EC 5.1.1.7) |
| BPHYT_RS01665 | N.D. |
| BPHYT_RS05020 | -3.8 |
| BPHYT_RS24370 | +0.2 |
| BPHYT_RS35135 | -0.1 |
Methionine adenosyltransferase:
L-methionine + ATP + H2O→S-adenosyl-L-methionine + diphosphate + phosphate (EC 2.5.1.6) |
| BPHYT_RS01675 | N.D. |
Diaminopimelate decarboxylase:
meso-diaminopimelate + H+→L-lysine + CO2 (EC 4.1.1.20) |
| BPHYT_RS00645 | -0.1 |
| BPHYT_RS17930 | +0.1 |
| BPHYT_RS35090 | +0.3 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information