MetaCyc Pathway: partial TCA cycle (obligate autotrophs) in Pseudomonas fluorescens FW300-N1B4

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Reactions and Genes methylglyoxal 0.008 vol%
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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
Pf1N1B4_3051 -0.1
Citrate (Si)-synthase:
oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
Pf1N1B4_3676 N.D.
oxaloacetate[in] + an electron-transfer quinol→(S)-malate[in] + an electron-transfer quinone (EC 1.1.5.4)
Pf1N1B4_2939 +0.4
Pf1N1B4_4189 +0.3
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
Pf1N1B4_3821 +0.5
Pf1N1B4_3888 +0.1
Pf1N1B4_4564 N.D.
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
Pf1N1B4_1088 N.D.
Pf1N1B4_367 +1.2
Pf1N1B4_683 +1.0
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
Pf1N1B4_3821 +0.5
Pf1N1B4_3888 +0.1
Pf1N1B4_4564 N.D.
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + an electron-transfer quinol→succinate[in] + an electron-transfer quinone (EC 1.3.5.1)
Pf1N1B4_3678 N.D.
Pf1N1B4_3679 N.D.
Pf1N1B4_3680 N.D.
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
Pf1N1B4_4050 N.D.
Pf1N1B4_4051 -0.5
Pf1N1B4_4052 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information