MetaCyc Pathway: ketolysis in Pedobacter sp. GW460-11-11-14-LB5

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Reactions and Genes L-Valine (N)
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+ (EC 1.1.1.30)
CA265_RS04230 +0.1
CA265_RS08355 -0.0
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate (EC 2.8.3.5)
CA265_RS06305 -0.1
CA265_RS06310 -0.0
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
CA265_RS06590 -0.0
CA265_RS17585 +2.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information