MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Shewanella amazonensis SB2B

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Reactions and Genes Glycine (N)
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Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+
(EC 1.1.1.95)
Sama_2811 -0.2
Sama_2949 -0.0
Sama_3039 -1.1
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamateO-phospho-L-serine + 2-oxoglutarate
(EC 2.6.1.52)
Sama_1732 N.D.
Sama_3277 -0.1
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate
(EC 3.1.3.3)
Sama_0978 -0.5
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O
(EC 2.1.2.1)
Sama_1014 (glyA) -3.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information