MetaCyc Pathway: stearate biosynthesis I (animals) in Shewanella oneidensis MR-1

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Reactions and Genes Tween 20 (C)
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Long-chain-fatty-acid--CoA ligase:
palmitate + ATP + coenzyme A→palmitoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
SO0075 -0.4
SO1971 -0.3
SO2581 (fadD-1) -1.8
SO3664 (fadD-2) -3.4
palmitoyl-CoA + malonyl-CoA + H+→3-oxooctadecanoyl-CoA + CO2 + coenzyme A (EC 2.3.1.199)
No genes
3-oxooctadecanoyl-CoA + NADPH + H+→(3R)-3-hydroxyoctadecanoyl-CoA + NADP+
No genes
(3R)-3-hydroxyoctadecanoyl-CoA→(2E)-octadec-2-enoyl-CoA + H2O (EC 4.2.1.119)
No genes
(2E)-octadec-2-enoyl-CoA + NADPH + H+→stearoyl-CoA + NADP+
No genes
Palmitoyl-CoA hydrolase:
stearoyl-CoA + H2O→stearate + coenzyme A + H+ (EC 3.1.2.2)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information