MetaCyc Pathway: cytosolic NADPH production (yeast) in Shewanella amazonensis SB2B

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Reactions and Genes L-Threonine (N)
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NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29)
Sama_2157 -1.7
Sama_2438 (ppnK) N.D.
NADH kinase:
NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29)
No genes
Glucose-6-phosphate dehydrogenase:
NADP+ + D-glucopyranose 6-phosphate→NADPH + 6-phospho D-glucono-1,5-lactone + H+ (EC 1.1.1.49)
Sama_1812 N.D.
Isocitrate dehydrogenase (NADP(+)):
NADP+ + D-threo-isocitrate→NADPH + 2-oxoglutarate + CO2 (EC 1.1.1.42)
Sama_2059 -2.1
Aldehyde dehydrogenase (NADP(+)):
NADP+ + acetaldehyde + H2O→NADPH + acetate + 2 H+ (EC 1.2.1.4)
Sama_1529 -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information