MetaCyc Pathway: L-histidine degradation VI in Burkholderia phytofirmans PsJN

Reactions and Genes	24hr PHYTO4 MOI 10
Histidine ammonia-lyase: L-histidine→urocanate + ammonium (EC 4.3.1.3)
BPHYT_RS07555	+0.2
BPHYT_RS15165	+2.1
BPHYT_RS24020	-0.0
Urocanate hydratase (in reverse): urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
BPHYT_RS07565	-0.2
Imidazolonepropionase: 4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
BPHYT_RS07575	+0.2
4-imidazolone-5-propanoate + dioxygen + H2O→hydantoin-5-propanoate + hydrogen peroxide
No genes
4-imidazolone-5-propanoate + H2O→formyl-L-isoglutamine (spontaneous)
No genes
4-imidazolone-5-propanoate + a reduced two electron carrier + dioxygen + H2O→4-oxoglutaramate + ammonium + an oxidized electron carrier + formate (spontaneous)
No genes
formyl-L-isoglutamine + H2O→L-isoglutamine + formate (spontaneous)
No genes
4-oxoglutaramate + H2O→2-oxoglutarate + ammonium (spontaneous)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information