MetaCyc Pathway: γ-glutamyl cycle in Burkholderia phytofirmans PsJN

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Reactions and Genes Rhizosphere from sorghum RTx_430 plants, grown 2 months, low phosphate; Rep 1
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5-oxoprolinase (ATP-hydrolyzing):
5-oxo-L-proline + ATP + 2 H2O→L-glutamate + ADP + H+ + phosphate (EC 3.5.2.9)
BPHYT_RS18635 -0.9
Glutamate--cysteine ligase:
L-glutamate + L-cysteine + ATP→γ-L-glutamyl-L-cysteine + ADP + H+ + phosphate (EC 6.3.2.2)
BPHYT_RS00520 -0.3
BPHYT_RS02555 -1.4
BPHYT_RS19565 +0.2
BPHYT_RS19680 -3.2
Glutathione synthase:
γ-L-glutamyl-L-cysteine + ATP + glycine→glutathione + ADP + H+ + phosphate (EC 6.3.2.3)
BPHYT_RS02560 -3.4
Gamma-glutamyltransferase:
glutathione + a proteinogenic amino acid→an α-(γ-L-glutamyl)-L-amino acid + L-cysteinylglycine (EC 2.3.2.2)
BPHYT_RS13995 +0.1
BPHYT_RS16465 +0.1
BPHYT_RS21360 +0.1
BPHYT_RS23080 +0.1
BPHYT_RS26100 -0.2
an α-(γ-L-glutamyl)-L-amino acid→5-oxo-L-proline + an L-amino acid (EC 4.3.2.9)
No genes
Cytosol nonspecific dipeptidase:
L-cysteinylglycine + H2O→L-cysteine + glycine (EC 3.4.13.18)
BPHYT_RS04795 -0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information