MetaCyc Pathway: dTDP-β-D-fucofuranose biosynthesis in Klebsiella michiganensis M5al

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Reactions and Genes K. M5a1 KLEB26 MOI 0.1
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Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24)
BWI76_RS01105 +1.8
BWI76_RS19060 +0.8
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O (EC 4.2.1.46)
BWI76_RS18995 N.D.
BWI76_RS19065 +0.5
dTDP-4-dehydro-6-deoxyglucose reductase (in reverse):
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + NAD(P)H + H+→dTDP-α-D-fucopyranose + NAD(P)+ (EC 1.1.1.266)
No genes
dTDP-α-D-fucopyranose→dTDP-β-D-fucofuranose (EC 5.4.99.59)
BWI76_RS18975 +1.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information