MetaCyc Pathway: ethanol degradation III in Mycobacterium tuberculosis H37Rv

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Reactions and Genes D,L-Malic Acid 10 mM (C)
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ethanol + dioxygen + a reduced [NADPH-hemoprotein reductase]→acetaldehyde + an oxidized [NADPH-hemoprotein reductase] + 2 H2O
No genes
Aldehyde dehydrogenase (NAD(+)):
acetaldehyde + NAD+ + H2O→acetate + NADH + 2 H+
(EC 1.2.1.3)
Rv0147 +0.2
Rv0223c +0.1
Rv0458 -0.4
Rv0768 -0.2
Rv1731 -0.0
Rv3293 +0.2
Acetate--CoA ligase:
acetate + ATP + coenzyme A→acetyl-CoA + AMP + diphosphate
(EC 6.2.1.1)
Rv3667 -1.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information