MetaCyc Pathway: phosphatidate biosynthesis (yeast) in Mycobacterium tuberculosis H37Rv

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Reactions and Genes 7H9 with Meropenem 9.6 ug/mL
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Glycerone-phosphate O-acyltransferase:
glycerone phosphate + oleoyl-CoA→1-oleoyl-2-lyso-glycerone phosphate + coenzyme A (EC 2.3.1.42)
No genes
Acylglycerone-phosphate reductase (in reverse):
1-oleoyl-2-lyso-glycerone phosphate + NADPH + H+→1-oleoyl-sn-glycerol 3-phosphate + NADP+ (EC 1.1.1.101)
No genes
1-acylglycerol-3-phosphate O-acyltransferase:
1-oleoyl-sn-glycerol 3-phosphate + oleoyl-CoA→bisoleoyl phosphatidate + coenzyme A (EC 2.3.1.51)
Rv2182c N.D.
Rv2483c -0.1
Rv3026c +0.2
Rv3814c -1.3
Rv3815c -0.4
Rv3816c +0.0
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + oleoyl-CoA→1-oleoyl-sn-glycerol 3-phosphate + coenzyme A (EC 2.3.1.15)
Rv1551 -0.1
Rv2482c +0.1
Glycerol-3-phosphate dehydrogenase (NAD(+)) (in reverse):
glycerone phosphate + NADH + H+→sn-glycerol 3-phosphate + NAD+ (EC 1.1.1.8)
Rv0564c +0.5
Rv2982c -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information