MetaCyc Pathway: superpathway of N-acetylneuraminate degradation in Enterobacter sp. TBS_079

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Reactions and Genes Plant=SorghumBicolor_Rtx430; PlantTreatment=None; Sample=rhizosphere; GrowthSubstrate=0.5X_MS_agar; Collection=outgrowth_LB_Kan50; Time=28_days; NumberPlantsPooled=4; CocultureWith=Inquilinus sp. 005-A5
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N-acetyl-β-neuraminate→aceneuramate (EC 5.1.3.24)
No genes
N-acetylneuraminate lyase:
aceneuramate→N-acetyl-D-mannosamine + pyruvate (EC 4.1.3.3)
No genes
N-acylmannosamine kinase:
N-acetyl-D-mannosamine + ATP→N-acetyl-D-mannosamine 6-phosphate + ADP + H+ (EC 2.7.1.60)
No genes
N-acylglucosamine-6-phosphate 2-epimerase:
N-acetyl-D-mannosamine 6-phosphate→N-acetyl-D-glucosamine 6-phosphate (EC 5.1.3.9)
MPMX20_03646 -0.0
N-acetylglucosamine-6-phosphate deacetylase:
N-acetyl-D-glucosamine 6-phosphate + H2O→D-glucosamine 6-phosphate + acetate (EC 3.5.1.25)
MPMX20_01323 -2.2
MPMX20_04044 +0.2
Glucosamine-6-phosphate deaminase:
D-glucosamine 6-phosphate + H2O→β-D-fructofuranose 6-phosphate + ammonium (EC 3.5.99.6)
MPMX20_01324 -0.4
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
MPMX20_01891 -0.1
MPMX20_04552 -2.6
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
MPMX20_00298 +0.3
MPMX20_03071 +0.9
MPMX20_03777 N.D.
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
MPMX20_00514 -1.1
MPMX20_00973 -0.0
MPMX20_01393 +0.4
MPMX20_04544 +0.1
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
MPMX20_04548 N.D.
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
MPMX20_01844 N.D.
MPMX20_02195 -0.6
MPMX20_02688 +0.5
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
MPMX20_03778 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
MPMX20_00121 +0.5
MPMX20_00702 -0.2
MPMX20_01382 -1.3
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
MPMX20_01382 -1.3
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
MPMX20_03650 N.D.
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
MPMX20_01951 +0.3
MPMX20_02759 +0.0
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
MPMX20_01922 -0.3
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
MPMX20_01463 +0.2
MPMX20_01464 +0.2
MPMX20_01561 -1.0
MPMX20_01562 -1.2
MPMX20_03448 -0.7
MPMX20_04018 +0.2
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
MPMX20_02589 -0.1
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
MPMX20_03227 -1.3
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
MPMX20_02754 -1.1
MPMX20_03226 -1.3
MPMX20_04019 -0.3
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
MPMX20_00006 -0.0
MPMX20_02209 -0.1
MPMX20_02371 -0.0
MPMX20_02515 +0.9
MPMX20_02589 -0.1
MPMX20_04122 -0.2
MPMX20_04159 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information