MetaCyc Pathway: purine nucleobases degradation II (anaerobic) in Rhodopseudomonas palustris CGA009

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Reactions and Genes PM with Formate and Sodium bicarbonate anaerobic with light
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Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium
(EC 3.5.4.3)
TX73_015070 -0.0
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→6,8-dihydroxypurine + NADH + H+
(EC 1.17.1.4)
TX73_003475 +0.2
Xanthine dehydrogenase:
purine + NAD+ + H2O→8-hydroxypurine + NADH + H+
(EC 1.17.1.4)
TX73_003475 +0.2
8-hydroxypurine + NAD+ + H2O→6,8-dihydroxypurine + NADH + H+
No genes
Xanthine dehydrogenase:
6,8-dihydroxypurine + NAD+ + H2O→urate + NADH + H+
(EC 1.17.1.4)
TX73_003475 +0.2
Xanthine dehydrogenase (in reverse):
urate + NADH + H+→xanthine + NAD+ + H2O
(EC 1.17.1.4)
TX73_003475 +0.2
xanthine + H2O→5-ureidoimidazole-4-carboxylate + H+
No genes
5-ureidoimidazole-4-carboxylate + 2 H+ + H2O→5-aminoimidazole-4-carboxylate + CO2 + ammonium
No genes
5-aminoimidazole-4-carboxylate→CO2 + 4-aminoimidazole
No genes
Aminoimidazolase:
4-aminoimidazole + H+ + H2O→3,5-dihydro-4H-imidazol-4-one + ammonium
(EC 3.5.4.8)
No genes
3,5-dihydro-4H-imidazol-4-one + H2ON-formimino-glycine (spontaneous)
No genes
Glycine formimidoyltransferase (in reverse):
N-formimino-glycine + a tetrahydrofolate→5-formimidoyltetrahydrofolate + glycine
(EC 2.1.2.4)
No genes
Formimidoyltetrahydrofolate cyclodeaminase:
5-formimidoyltetrahydrofolate + 2 H+→a 5,10-methenyltetrahydrofolate + ammonium
(EC 4.3.1.4)
No genes
Methenyltetrahydrofolate cyclohydrolase:
a 5,10-methenyltetrahydrofolate + H2O→an N10-formyltetrahydrofolate + H+
(EC 3.5.4.9)
TX73_002145 N.D.
Methylenetetrahydrofolate dehydrogenase (NADP(+)) (in reverse):
a 5,10-methenyltetrahydrofolate + NADPH→a 5,10-methylenetetrahydrofolate + NADP+
(EC 1.5.1.5)
TX73_002145 N.D.
Formyltetrahydrofolate deformylase:
an N10-formyltetrahydrofolate + H2O→formate + H+ + a tetrahydrofolate
(EC 3.5.1.10)
TX73_020890 +0.2
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate
(EC 2.1.2.1)
TX73_008155 +0.1
TX73_012225 +0.0
TX73_014115 N.D.
TX73_014480 +0.0
formate + NAD+→CO2 + NADH (EC 1.17.1.9)
TX73_001975 -0.0
TX73_003800 -3.0
TX73_021925 -0.0
L-serine ammonia-lyase:
L-serine→2-aminoprop-2-enoate + H2O
(EC 4.3.1.17)
No genes
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate
(spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
TX73_001930 -0.2
TX73_012185 -0.0
TX73_018475 +0.2
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
TX73_001930 -0.2
TX73_012185 -0.0
TX73_018475 +0.2
Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→CO2 + acetyl-CoA + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster
(EC 1.2.7.1)
No genes
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A
(EC 2.3.1.8)
TX73_023725 +0.0
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP
(EC 2.7.2.1; 2.7.2.15)
TX73_023720 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information