MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Rhodopseudomonas palustris CGA009

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Reactions and Genes 4-Hydroxybenzoate (C)
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glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)
TX73_000560 +0.0
TX73_002485 +0.1
TX73_003390 -4.7
TX73_004045 +0.1
TX73_004610 -0.2
TX73_004615 -0.1
TX73_008650 -0.1
TX73_008655 +0.2
TX73_008935 +0.3
TX73_011140 +0.1
TX73_012495 +0.3
TX73_015900 N.D.
TX73_016995 +0.2
TX73_017080 -0.0
TX73_017465 -0.1
TX73_017980 -0.5
TX73_018405 +0.1
TX73_018410 -0.1
TX73_020990 -0.5
TX73_023875 +0.3
TX73_024180 -0.2
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)
TX73_002210 N.D.
TX73_010415 -0.1
TX73_015090 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)
TX73_002220 N.D.
TX73_006160 +0.1
TX73_010005 -0.1
TX73_011140 +0.1
TX73_016095 +0.1
TX73_023730 -0.2
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
TX73_015415 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information