MetaCyc Pathway: L-glutamate and L-glutamine biosynthesis in Rhodopseudomonas palustris CGA009

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Reactions and Genes 4-Hydroxybenzoate (C)
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Glutamate dehydrogenase (NAD(P)(+)) (in reverse):
2-oxoglutarate + ammonium + NAD(P)H + H+→L-glutamate + NAD(P)+ + H2O (EC 1.4.1.3)
No genes
Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
TX73_002450 +0.4
Glutamate synthase (NADH) (in reverse):
2-oxoglutarate + L-glutamine + NADH + H+→2 L-glutamate + NAD+ (EC 1.4.1.14)
TX73_004595 N.D.
TX73_024530 -0.0
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
TX73_002175 -0.1
TX73_002450 +0.4
TX73_003510 -4.1
TX73_003905 +0.0
TX73_004590 N.D.
TX73_004595 N.D.
TX73_006555 N.D.
TX73_007185 -0.2
TX73_007195 +0.1
TX73_007200 +0.2
TX73_007205 +0.1
TX73_007520 +0.2
TX73_007545 +0.1
TX73_008750 +0.1
TX73_009145 -0.2
TX73_010810 +0.2
TX73_011370 N.D.
TX73_012920 -0.0
TX73_014960 N.D.
TX73_016055 N.D.
TX73_016070 N.D.
TX73_016090 -0.9
TX73_020510 -0.1
TX73_021090 N.D.
TX73_021830 +0.2
TX73_023350 N.D.
TX73_024530 -0.0
Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
TX73_005065 +0.0
TX73_007190 -0.0
TX73_015390 N.D.
TX73_021820 +0.1
Glutamate dehydrogenase (NADP(+)) (in reverse):
2-oxoglutarate + ammonium + NADPH + H+→L-glutamate + NADP+ + H2O (EC 1.4.1.4)
No genes
Glutamate synthase (NADPH) (in reverse):
2-oxoglutarate + ammonia + NADPH + 2 H+→L-glutamate + NADP+ + H2O (EC 1.4.1.13; 1.4.1.14)
TX73_003510 -4.1
TX73_004590 N.D.
TX73_004595 N.D.
TX73_024530 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information