MetaCyc Pathway: 4-coumarate degradation (anaerobic) in Rhodopseudomonas palustris CGA009

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Reactions and Genes 4-Hydroxybenzoate (C)
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
TX73_008785 -0.1
TX73_009190 -0.0
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
TX73_009185 +0.1
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA→4-hydroxybenzaldehyde + acetyl-CoA (EC 4.1.2.61)
TX73_009185 +0.1
Vanillin dehydrogenase:
4-hydroxybenzaldehyde + NAD(P)+ + H2O→4-hydroxybenzoate + NAD(P)H + 2 H+ (EC 1.2.1.67)
No genes
4-hydroxybenzoate--CoA ligase:
4-hydroxybenzoate + ATP + coenzyme A→4-hydroxybenzoyl-CoA + AMP + diphosphate (EC 6.2.1.27)
TX73_003465 -0.3
4-hydroxybenzoyl-CoA + 2 H+ + a reduced 2[4Fe-4s] ferredoxin→benzoyl-CoA + an oxidized 2[4Fe-4s] ferredoxin + H2O (EC 1.1.7.1)
TX73_003470 -6.0
TX73_003475 -4.6
TX73_003480 -4.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information