MetaCyc Pathway: L-valine degradation I in Rhodopseudomonas palustris CGA009

Reactions and Genes	4-Hydroxybenzoate (C)
Branched-chain-amino-acid transaminase: L-valine + 2-oxoglutarate→3-methyl-2-oxobutanoate + L-glutamate (EC 2.6.1.42)
TX73_022650	N.D.
TX73_023855	-0.0
2-oxoisovalerate dehydrogenase (acylating): 3-methyl-2-oxobutanoate + coenzyme A + NAD+→isobutanoyl-CoA + CO2 + NADH (EC 1.2.1.25)
No genes
isobutanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→methylacrylyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.5)
No genes
methylacrylyl-CoA + H2O→(S)-3-hydroxy-isobutanoyl-CoA (EC 4.2.1.150)
TX73_001990	+0.1
TX73_002165	-0.0
TX73_002395	-0.1
TX73_002500	+0.5
TX73_002510	+0.3
TX73_003370	+0.0
TX73_004930	-0.1
TX73_006355	-0.1
TX73_007240	+0.1
TX73_008810	+0.1
TX73_009040	-0.1
TX73_009055	-0.1
TX73_009185	+0.1
TX73_009315	+2.1
TX73_011975	-0.2
TX73_014325	-0.2
TX73_017085	-0.3
TX73_017810	+0.1
TX73_017875	-0.4
TX73_019255	-0.3
TX73_019650	-0.0
TX73_022390	-0.0
TX73_022490	+0.3
3-hydroxyisobutyryl-CoA hydrolase: (S)-3-hydroxy-isobutanoyl-CoA + H2O→(S)-3-hydroxy-isobutanoate + coenzyme A + H+ (EC 3.1.2.4)
TX73_017840	+2.2
3-hydroxyisobutyrate dehydrogenase: (S)-3-hydroxy-isobutanoate + NAD+→(S)-methylmalonate-semialdehyde + NADH + H+ (EC 1.1.1.31)
TX73_004220	+0.3
TX73_010170	-0.1
TX73_017835	+0.1
TX73_018155	-0.2
TX73_019255	-0.3
(S)-3-amino-2-methylpropionate transaminase (in reverse): (S)-methylmalonate-semialdehyde + L-glutamate→(S)-3-amino-2-methylpropanoate + 2-oxoglutarate (EC 2.6.1.22)
TX73_012015	-0.1
Methylmalonate-semialdehyde dehydrogenase (acylating): (S)-methylmalonate-semialdehyde + coenzyme A + NAD+ + H2O→propanoyl-CoA + hydrogen carbonate + NADH + H+ (EC 1.2.1.27)
TX73_017860	-0.9

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information