MetaCyc Pathway: superpathway of unsaturated fatty acids biosynthesis (E. coli) in Rhodopseudomonas palustris CGA009

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Reactions and Genes 4-Hydroxybenzoate (C)
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3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydecanoyl-[acp]→a (2E)-dec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
TX73_002210 N.D.
TX73_010415 -0.3
TX73_015090 N.D.
Trans-2-decenoyl-[acyl-carrier-protein] isomerase:
a (2E)-dec-2-enoyl-[acp]→a (3Z)-dec-3-enoyl-[acp] (EC 5.3.3.14)
TX73_002210 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (3Z)-dec-3-enoyl-[acp] + a malonyl-[acp] + H+→a (5Z)-3-oxododec-5-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
TX73_002215 N.D.
TX73_010405 N.D.
TX73_010410 N.D.
TX73_015890 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (5Z)-3-oxododec-5-enoyl-[acp] + NADPH + H+→a (3R,5Z)-3-hydroxydodec-5-enoyl-[acp] + NADP+ (EC 1.1.1.100)
TX73_000560 -0.0
TX73_002485 +0.2
TX73_003390 -3.7
TX73_004045 +0.0
TX73_004610 +0.2
TX73_004615 +0.0
TX73_008650 +0.1
TX73_008655 +0.4
TX73_008935 -0.2
TX73_011140 -0.3
TX73_012495 +0.1
TX73_015900 N.D.
TX73_016995 +0.1
TX73_017080 -0.1
TX73_017465 -0.2
TX73_017980 -0.1
TX73_018405 -0.2
TX73_018410 +0.1
TX73_020990 -0.5
TX73_023875 +0.5
TX73_024180 -0.3
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,5Z)-3-hydroxydodec-5-enoyl-[acp]→a (2E,5Z)-dodeca-3,5-dienoyl-[acp] + H2O (EC 4.2.1.59)
TX73_002210 N.D.
TX73_010415 -0.3
TX73_015090 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,5Z)-dodeca-3,5-dienoyl-[acp] + NADH + H+→a (5Z)-dodec-5-enoyl-[acp] + NAD+ (EC 1.3.1.9)
TX73_002220 N.D.
TX73_006160 +0.2
TX73_010005 -0.1
TX73_011140 -0.3
TX73_016095 -0.5
TX73_023730 -0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (5Z)-dodec-5-enoyl-[acp] + a malonyl-[acp] + H+→a (7Z)-3-oxotetradec-7-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
TX73_002215 N.D.
TX73_010405 N.D.
TX73_010410 N.D.
TX73_015890 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (7Z)-3-oxotetradec-7-enoyl-[acp] + NADPH + H+→a (3R,7Z)-3-hydroxytetradec-7-enoyl-[acp] + NADP+ (EC 1.1.1.100)
TX73_000560 -0.0
TX73_002485 +0.2
TX73_003390 -3.7
TX73_004045 +0.0
TX73_004610 +0.2
TX73_004615 +0.0
TX73_008650 +0.1
TX73_008655 +0.4
TX73_008935 -0.2
TX73_011140 -0.3
TX73_012495 +0.1
TX73_015900 N.D.
TX73_016995 +0.1
TX73_017080 -0.1
TX73_017465 -0.2
TX73_017980 -0.1
TX73_018405 -0.2
TX73_018410 +0.1
TX73_020990 -0.5
TX73_023875 +0.5
TX73_024180 -0.3
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,7Z)-3-hydroxytetradec-7-enoyl-[acp]→a (2E,7Z)-tetradeca-2,7-dienoyl-[acp] + H2O (EC 4.2.1.59)
TX73_002210 N.D.
TX73_010415 -0.3
TX73_015090 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,7Z)-tetradeca-2,7-dienoyl-[acp] + NADH + H+→a (7Z)-tetradec-7-enoyl-[acp] + NAD+ (EC 1.3.1.9)
TX73_002220 N.D.
TX73_006160 +0.2
TX73_010005 -0.1
TX73_011140 -0.3
TX73_016095 -0.5
TX73_023730 -0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (7Z)-tetradec-7-enoyl-[acp] + a malonyl-[acp] + H+→a (9Z)-3-oxohexadec-9-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
TX73_002215 N.D.
TX73_010405 N.D.
TX73_010410 N.D.
TX73_015890 N.D.
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (9Z)-3-oxohexadec-9-enoyl-[acp] + NADPH + H+→a (3R,9Z)-3-hydroxyhexadec-9-enoyl-[acp] + NADP+ (EC 1.1.1.100)
TX73_000560 -0.0
TX73_002485 +0.2
TX73_003390 -3.7
TX73_004045 +0.0
TX73_004610 +0.2
TX73_004615 +0.0
TX73_008650 +0.1
TX73_008655 +0.4
TX73_008935 -0.2
TX73_011140 -0.3
TX73_012495 +0.1
TX73_015900 N.D.
TX73_016995 +0.1
TX73_017080 -0.1
TX73_017465 -0.2
TX73_017980 -0.1
TX73_018405 -0.2
TX73_018410 +0.1
TX73_020990 -0.5
TX73_023875 +0.5
TX73_024180 -0.3
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,9Z)-3-hydroxyhexadec-9-enoyl-[acp]→a (2E,9Z)-hexadeca-2,9-dienoyl-[acp] + H2O (EC 4.2.1.59)
TX73_002210 N.D.
TX73_010415 -0.3
TX73_015090 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,9Z)-hexadeca-2,9-dienoyl-[acp] + NADH + H+→a palmitoleoyl-[acp] + NAD+ (EC 1.3.1.9)
TX73_002220 N.D.
TX73_006160 +0.2
TX73_010005 -0.1
TX73_011140 -0.3
TX73_016095 -0.5
TX73_023730 -0.1
Beta-ketoacyl-acyl-carrier-protein synthase II:
a palmitoleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxooctadec-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179)
TX73_010405 N.D.
TX73_010410 N.D.
TX73_015890 N.D.
Oleoyl-[acyl-carrier-protein] hydrolase:
a palmitoleoyl-[acp] + H2O→palmitoleate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxooctadec-11-enoyl-[acp] + NADPH + H+→a (3R,11Z)-3-hydroxyoctadec-11-enoyl-[acp] + NADP+ (EC 1.1.1.100)
TX73_000560 -0.0
TX73_002485 +0.2
TX73_003390 -3.7
TX73_004045 +0.0
TX73_004610 +0.2
TX73_004615 +0.0
TX73_008650 +0.1
TX73_008655 +0.4
TX73_008935 -0.2
TX73_011140 -0.3
TX73_012495 +0.1
TX73_015900 N.D.
TX73_016995 +0.1
TX73_017080 -0.1
TX73_017465 -0.2
TX73_017980 -0.1
TX73_018405 -0.2
TX73_018410 +0.1
TX73_020990 -0.5
TX73_023875 +0.5
TX73_024180 -0.3
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxyoctadec-11-enoyl-[acp]→a (2E,11Z)-octadeca-2,11-dienoyl-[acp] + H2O (EC 4.2.1.59)
TX73_002210 N.D.
TX73_010415 -0.3
TX73_015090 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-octadeca-2,11-dienoyl-[acp] + NADH + H+→a cis-vaccenoyl-[acp] + NAD+ (EC 1.3.1.9)
TX73_002220 N.D.
TX73_006160 +0.2
TX73_010005 -0.1
TX73_011140 -0.3
TX73_016095 -0.5
TX73_023730 -0.1
Oleoyl-[acyl-carrier-protein] hydrolase:
a cis-vaccenoyl-[acp] + H2O→cis-vaccenate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information