MetaCyc Pathway: 3-phenylpropanoate degradation in Rhodopseudomonas palustris CGA009

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Reactions and Genes 4-Hydroxybenzoate (C)
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3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
TX73_001990 +0.1
TX73_002165 -0.0
TX73_002395 -0.1
TX73_002500 +0.5
TX73_002510 +0.3
TX73_003370 +0.0
TX73_003500 +0.2
TX73_004220 +0.3
TX73_004930 -0.1
TX73_006355 -0.1
TX73_007240 +0.1
TX73_008780 -0.1
TX73_008810 +0.1
TX73_009040 -0.1
TX73_009055 -0.1
TX73_009075 +0.2
TX73_009185 +0.1
TX73_009315 +2.1
TX73_011065 +0.2
TX73_011975 -0.2
TX73_014325 -0.2
TX73_017085 -0.3
TX73_017810 +0.1
TX73_017840 +2.2
TX73_017875 -0.4
TX73_019255 -0.3
TX73_019650 -0.0
TX73_022390 -0.0
TX73_022490 +0.3
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
TX73_004220 +0.3
TX73_008775 -0.2
TX73_011910 +0.1
TX73_018155 -0.2
TX73_019255 -0.3
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
TX73_002660 -0.0
TX73_002750 -0.6
TX73_004215 +0.3
TX73_008765 -0.0
TX73_011915 +0.7
TX73_017920 +0.0
TX73_017940 +0.1
TX73_019245 -0.1
TX73_022530 -0.2
Benzoyl-CoA 3-monooxygenase:
benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
No genes
Maleylpyruvate isomerase:
3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
No genes
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
TX73_020685 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information