MetaCyc Pathway: coenzyme B/coenzyme M regeneration I (methanophenazine-dependent) in Methanococcus maripaludis JJ

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Reactions and Genes H2 McCas, 5g/L bicarb, 40 psi H2CO2
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Coenzyme F420 hydrogenase:
H2 + an oxidized factor 420→a reduced factor 420
(EC 1.12.98.1)
MMJJ_RS00880 +0.1
MMJJ_RS00890 +0.4
MMJJ_RS00895 -0.3
MMJJ_RS05010 +1.5
MMJJ_RS07220 +1.4
MMJJ_RS07225 +1.6
MMJJ_RS07235 +1.7
Methanosarcina-phenazine hydrogenase:
H2 + methanophenazine→dihydromethanophenazine
(EC 1.12.98.3)
No genes
a reduced factor 420 + methanophenazine→dihydromethanophenazine + an oxidized factor 420 (EC 1.5.98.3)
No genes
CoB--CoM heterodisulfide reductase (in reverse):
dihydromethanophenazine + CoB-CoM heterodisulfide→coenzyme B + coenzyme M + methanophenazine
(EC 1.8.98.1)
MMJJ_RS00855 -0.2
MMJJ_RS05620 -3.0
MMJJ_RS08395 -0.0
MMJJ_RS08400 -0.8
MMJJ_RS08915 -0.8
MMJJ_RS08920 -1.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information