| Reactions and Genes | L-Lysine (C) |
|---|
| remove |
| a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| AO356_02330 | N.D. |
| AO356_04640 | +0.0 |
| AO356_10120 | -0.0 |
| AO356_12440 | +0.0 |
| AO356_17825 | +0.2 |
| AO356_20400 | +0.0 |
| AO356_20420 | N.D. |
| AO356_25890 | -0.4 |
| AO356_26360 | -0.8 |
| AO356_26370 | -0.1 |
| AO356_26645 | +0.1 |
| AO356_27920 | -0.2 |
| AO356_30295 | +0.2 |
| AO356_30355 | -0.3 |
| AO356_30360 | -0.2 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| AO356_02330 | N.D. |
| AO356_10120 | -0.0 |
| AO356_13845 | +0.0 |
| AO356_20400 | +0.0 |
| AO356_30295 | +0.2 |
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA (EC 2.3.1.16) |
| AO356_02325 | -1.8 |
| AO356_03560 | -0.2 |
| AO356_04930 | -0.6 |
| AO356_08090 | -0.3 |
| AO356_20395 | +0.5 |
| AO356_21640 | -4.3 |
| AO356_26350 | +0.9 |
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3) |
| AO356_19670 | N.D. |
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3) |
| AO356_02385 | +0.0 |
| AO356_20875 | -1.9 |
| AO356_24390 | N.D. |
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3) |
| AO356_02385 | +0.0 |
| AO356_20875 | -1.9 |
| AO356_24390 | N.D. |
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate (EC 4.1.3.1) |
| AO356_22080 | -4.3 |
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9) |
| AO356_14100 | -4.0 |
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1) |
| AO356_19675 | N.D. |
| AO356_19680 | N.D. |
| AO356_19685 | N.D. |
| AO356_19690 | N.D. |
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2) |
| AO356_03545 | N.D. |
| AO356_07075 | -1.9 |
| AO356_17810 | N.D. |
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38) |
| No genes |
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2 (EC 4.1.1.49) |
| AO356_10140 | +0.7 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information