MetaCyc Pathway: fatty acid β-oxidation I (generic) in Pseudomonas fluorescens FW300-N2C3

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Reactions and Genes L-Lysine (C)
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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
AO356_02330 N.D.
AO356_10120 -0.0
AO356_30295 +0.2
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
AO356_02330 N.D.
AO356_10120 -0.0
AO356_20400 +0.0
AO356_30295 +0.2
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
AO356_02330 N.D.
AO356_04640 +0.0
AO356_10120 -0.0
AO356_12440 +0.0
AO356_17825 +0.2
AO356_20400 +0.0
AO356_20420 N.D.
AO356_25890 -0.4
AO356_26360 -0.8
AO356_26370 -0.1
AO356_26645 +0.1
AO356_27920 -0.2
AO356_30295 +0.2
AO356_30355 -0.3
AO356_30360 -0.2
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
AO356_02330 N.D.
AO356_10120 -0.0
AO356_13845 +0.0
AO356_20400 +0.0
AO356_30295 +0.2
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
AO356_02325 -1.8
AO356_03560 -0.2
AO356_04930 -0.6
AO356_08090 -0.3
AO356_20395 +0.5
AO356_21640 -4.3
AO356_26350 +0.9

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information