MetaCyc Pathway: methylglyoxal degradation IV in Rahnella sp. WP5

Reactions and Genes	D,L-Lactate (C)
	remove
Methylglyoxal reductase (NADPH-dependent) (in reverse): methylglyoxal + NADPH + H⁺→(S)-lactaldehyde + NADP⁺ (EC 1.1.1.283)
EX31_RS20820	-0.3
Lactaldehyde dehydrogenase: (S)-lactaldehyde + NAD⁺ + H₂O→(S)-lactate + NADH + 2 H⁺ (EC 1.2.1.22)
EX31_RS00250	-0.6
EX31_RS04190	+0.1
EX31_RS12300	+0.1
(S)-lactate_[in] + an electron-transfer quinone→pyruvate_[in] + an electron-transfer quinol (EC 1.1.5.M6)
EX31_RS00640	-3.1

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Pathway details at MetaCyc
Fitness data for 5 genes
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All MetaCyc pathways for Rahnella sp. WP5

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information