MetaCyc Pathway: incomplete reductive TCA cycle in Rahnella sp. WP5

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Reactions and Genes D,L-Lactate (C)
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Pyruvate synthase (in reverse):
acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
EX31_RS06430 -0.6
EX31_RS15420 +0.1
Pyruvate carboxylase:
pyruvate + ATP + hydrogen carbonate→oxaloacetate + ADP + H+ + phosphate (EC 6.4.1.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
EX31_RS01150 +0.4
EX31_RS08645 -3.5
EX31_RS18665 -0.0
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
EX31_RS01160 +0.1
EX31_RS06965 -0.2
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
EX31_RS08900 +0.0
EX31_RS08905 -0.3
EX31_RS08910 -0.0
EX31_RS08915 +0.0
Succinate--CoA ligase (ADP-forming):
succinate + ATP + coenzyme A→succinyl-CoA + ADP + phosphate (EC 6.2.1.5)
EX31_RS23450 -0.8
EX31_RS23455 -0.1
2-oxoglutarate synthase (in reverse):
succinyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2-oxoglutarate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.3)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information