MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Rahnella sp. WP5

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Reactions and Genes D,L-Lactate (C)
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2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
EX31_RS03465 N.D.
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
EX31_RS23450 -0.8
EX31_RS23455 -1.1
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
No genes
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2)
EX31_RS01160 +0.1
EX31_RS06965 -0.2
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
EX31_RS01150 +0.3
EX31_RS08645 -3.5
EX31_RS18665 +0.2
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
EX31_RS03060 -0.1
EX31_RS05810 -0.1
EX31_RS10390 -0.1
EX31_RS11565 +0.2
EX31_RS13555 -0.1
EX31_RS15520 -0.3
EX31_RS17445 +0.5
EX31_RS17525 +0.2
EX31_RS18145 +0.4
EX31_RS19445 +0.2
EX31_RS19635 -0.0
EX31_RS23055 +0.7
EX31_RS23680 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information