MetaCyc Pathway: ketolysis in Pseudomonas fluorescens FW300-N2C3

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Reactions and Genes L-Lysine (C)
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+ (EC 1.1.1.30)
AO356_00420 -0.2
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate (EC 2.8.3.5)
AO356_21645 +0.1
AO356_21650 +0.3
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
AO356_02325 -0.5
AO356_03560 -0.1
AO356_04930 -0.6
AO356_08090 +0.0
AO356_20395 +0.5
AO356_21640 -4.0
AO356_26350 -0.6
AO356_30300 +0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information