MetaCyc Pathway: 6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus) in Methanococcus maripaludis JJ

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Reactions and Genes H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2
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GTP + H2O→7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + diphosphate + H+ (EC 3.5.4.39)
MMJJ_RS05265 N.D.
7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O→7,8-dihydroneopterin 3'-phosphate + H+ (EC 3.1.4.56)
MMJJ_RS04115 -1.3
7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O→7,8-dihydroneopterin 2'-phosphate + H+ (EC 3.1.4.56)
MMJJ_RS04115 -1.3
7,8-dihydroneopterin 3'-phosphate + H2O→D-erythro-7,8-dihydroneopterin + phosphate
No genes
7,8-dihydroneopterin 2'-phosphate + H2O→D-erythro-7,8-dihydroneopterin + phosphate
No genes
Dihydroneopterin aldolase:
D-erythro-7,8-dihydroneopterin→6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde
(EC 4.1.2.25)
MMJJ_RS04050 -1.6
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase:
6-(hydroxymethyl)-7,8-dihydropterin + ATP→(7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+
(EC 2.7.6.3)
MMJJ_RS02020 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information