MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Sinorhizobium meliloti 1021

Reactions and Genes	LB, pH8
2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
SMc01030	N.D.
SMc01031	N.D.
Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
SMc02480	N.D.
SMc02481	N.D.
Succinate dehydrogenase (ubiquinone): succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
SMc02465	N.D.
Fumarate hydratase (in reverse): fumarate + H2O→(S)-malate (EC 4.2.1.2)
SMc00149	N.D.
Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
SMc00169	+2.5
SMc02479	N.D.
Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
SM_b20039	-0.2
SMa0387	-0.0
SMa1495	-0.2
SMc00294	+0.4
SMc00490	+0.2
SMc01406	-0.5
SMc01578	+0.3
SMc01969	-1.7
SMc02251	-0.1
SMc02262	-0.1
SMc02393	+0.2
SMc04326	-0.1
SMc04386	-0.4

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information