MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Sinorhizobium meliloti 1021

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Reactions and Genes LB, pH8
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Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate
(EC 2.6.1.1)
SM_b20039 -0.2
SMa0387 -0.0
SMa1495 -0.2
SMc00294 +0.4
SMc00490 +0.2
SMc01406 -0.5
SMc01578 +0.3
SMc01969 -1.7
SMc02251 -0.1
SMc02262 -0.1
SMc02393 +0.2
SMc04326 -0.1
SMc04386 -0.4
Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate
(EC 4.3.1.1)
No genes
Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+
(EC 6.3.1.1)
No genes
Asparaginase:
L-asparagine + H2O→L-aspartate + ammonium
(EC 3.5.1.1; 3.5.1.38; 3.5.5.4)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information