MetaCyc Pathway: myo-inositol degradation I in Pseudomonas fluorescens FW300-N2C3

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Reactions and Genes m-Inositol (C)
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Inositol 2-dehydrogenase:
myo-inositol + NAD+→scyllo-inosose + NADH + H+ (EC 1.1.1.18)
AO356_23190 -4.9
AO356_23195 -1.2
AO356_23320 +0.4
AO356_27260 +0.1
AO356_29215 -0.2
Myo-inosose-2 dehydratase:
scyllo-inosose→3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O (EC 4.2.1.44)
AO356_23165 -5.8
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O→5-deoxy-D-glucuronate + H+ (EC 3.7.1.22)
AO356_23185 -4.8
5-deoxy-D-glucuronate→5-dehydro-2-deoxy-D-gluconate (EC 5.3.1.30)
AO356_23170 -5.9
5-dehydro-2-deoxygluconokinase:
5-dehydro-2-deoxy-D-gluconate + ATP→5-dehydro-2-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.92)
AO356_23160 -5.5
AO356_23170 -5.9
5-dehydro-2-deoxyphosphogluconate aldolase:
5-dehydro-2-deoxy-D-gluconate 6-phosphate→glycerone phosphate + 3-oxopropanoate (EC 4.1.2.29)
AO356_23160 -5.5
Malonate-semialdehyde dehydrogenase (acetylating):
3-oxopropanoate + coenzyme A + NAD+→acetyl-CoA + CO2 + NADH (EC 1.2.1.18)
AO356_07870 -0.0
AO356_07950 +0.0
AO356_23175 -5.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information