MetaCyc Pathway: L-histidine degradation II in Sinorhizobium meliloti 1021

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Reactions and Genes LB, pH6
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Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)
SM_b21165 -0.3
SMa0306 -0.3
SMc00669 +0.5
Urocanate hydratase (in reverse):
urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
SM_b21163 +1.0
Imidazolonepropionase:
4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
SM_b21166 +0.6
Formimidoylglutamate deiminase:
N-formimino-L-glutamate + H2O→N-formyl-L-glutamate + ammonium (EC 3.5.3.13)
SMc00673 +0.1
N-formylglutamate deformylase:
N-formyl-L-glutamate + H2O→L-glutamate + formate (EC 3.5.1.68)
SM_b21164 +0.6
SMc03098 -0.2
SMc04043 +1.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information