MetaCyc Pathway: CDP-4-dehydro-3,6-dideoxy-D-glucose biosynthesis in Sinorhizobium meliloti 1021

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Reactions and Genes Fusidic 0.0001 mg/ml
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Glucose-1-phosphate cytidylyltransferase:
α-D-glucopyranose 1-phosphate + CTP + H+→CDP-α-D-glucose + diphosphate (EC 2.7.7.33)
SM_b21058 +0.2
SM_b21059 -0.0
SM_b21416 -1.1
CDP-glucose 4,6-dehydratase:
CDP-α-D-glucose→CDP-4-dehydro-6-deoxy-α-D-glucose + H2O (EC 4.2.1.45)
SM_b21417 -1.0
CDP-4-dehydro-6-deoxyglucose reductase (in reverse):
CDP-4-dehydro-6-deoxy-α-D-glucose + NAD(P)H + H+→CDP-4-dehydro-3,6-dideoxy-α-D-glucose + NAD(P)+ + H2O (EC 1.17.1.1)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information