MetaCyc Pathway: GDP-mannose biosynthesis in Pseudomonas fluorescens FW300-N2E2

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Reactions and Genes Phosphomycin 0.004 mg/ml
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Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
Pf6N2E2_5150 +1.7
Mannose-6-phosphate isomerase (in reverse):
β-D-fructofuranose 6-phosphate→D-mannopyranose 6-phosphate (EC 5.3.1.8)
Pf6N2E2_2741 +0.5
Pf6N2E2_3574 +1.2
Pf6N2E2_5377 -1.0
Pf6N2E2_5763 +0.3
Phosphomannomutase (in reverse):
D-mannopyranose 6-phosphate→α-D-mannose 1-phosphate (EC 5.4.2.8)
Pf6N2E2_4374 -0.9
Mannose-1-phosphate guanylyltransferase:
α-D-mannose 1-phosphate + GTP + H+→GDP-α-D-mannose + diphosphate (EC 2.7.7.13)
Pf6N2E2_5377 -1.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information