MetaCyc Pathway: L-tyrosine degradation I in Ralstonia sp. UNC404CL21Col

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Reactions and Genes Beta-alanine (C)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
ABZR87_RS02495 -0.2
ABZR87_RS03260 -0.1
ABZR87_RS04630 -0.0
ABZR87_RS05850 +0.0
ABZR87_RS05985 -0.2
ABZR87_RS05990 -0.2
ABZR87_RS08250 +0.0
ABZR87_RS08830 -0.1
ABZR87_RS08860 -0.1
ABZR87_RS09455 -0.1
ABZR87_RS09835 -0.3
ABZR87_RS09935 -4.2
ABZR87_RS11440 -0.1
ABZR87_RS14645 +0.0
ABZR87_RS17005 -0.1
ABZR87_RS18535 -0.0
ABZR87_RS19655 -4.0
ABZR87_RS21785 -0.1
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
ABZR87_RS03395 -0.1
ABZR87_RS19800 -0.1
ABZR87_RS19825 +0.0
ABZR87_RS22710 +0.0
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
ABZR87_RS20850 +0.1
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
ABZR87_RS06920 +0.4
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
ABZR87_RS06915 +0.1
ABZR87_RS20855 +0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information